| MLB Pitching Statistics | |||||||||
| Player | IP | W | L | ERA | SV | SVO | K | BB | BAVG |
| Fernando Nieve | 36.2 | 3 | 3 | 2.95 | 0 | 0 | 23 | 19 | 0.263 |
| Brett Tomko | 36.2 | 4 | 1 | 2.95 | 0 | 0 | 22 | 6 | 0.230 |
| Daniel McCutchen | 36.1 | 1 | 2 | 4.21 | 0 | 0 | 19 | 11 | 0.271 |
| Scott Kazmir | 36.1 | 2 | 2 | 1.73 | 0 | 0 | 26 | 10 | 0.212 |
| Jon Garland | 36.1 | 3 | 2 | 2.72 | 0 | 0 | 26 | 9 | 0.262 |
| Wade Davis | 36.1 | 2 | 2 | 3.72 | 0 | 0 | 36 | 13 | 0.243 |
| Randy Choate | 36.1 | 1 | 0 | 3.47 | 5 | 5 | 28 | 11 | 0.214 |
| Tony Peña | 36.0 | 1 | 2 | 3.75 | 1 | 2 | 29 | 9 | 0.272 |
| Tyler Walker | 35.1 | 2 | 1 | 3.06 | 0 | 0 | 27 | 9 | 0.230 |
| Julián Tavárez | 35.0 | 3 | 7 | 4.89 | 1 | 2 | 32 | 27 | 0.250 |
| Jeff Samardzija | 34.2 | 1 | 3 | 7.53 | 0 | 0 | 21 | 15 | 0.329 |
| Jonathan Albaladejo | 34.1 | 5 | 1 | 5.24 | 0 | 1 | 21 | 16 | 0.306 |
| Eddie Bonine | 34.1 | 1 | 1 | 4.46 | 0 | 0 | 19 | 12 | 0.308 |
| Joe Smith | 34.0 | 0 | 0 | 3.44 | 0 | 1 | 30 | 13 | 0.236 |
| Sergio Romo | 34.0 | 5 | 2 | 3.97 | 2 | 2 | 41 | 11 | 0.233 |
| Paul Byrd | 34.0 | 1 | 3 | 5.82 | 0 | 0 | 11 | 11 | 0.331 |
| Tony Peña | 34.0 | 5 | 3 | 4.24 | 1 | 2 | 26 | 11 | 0.295 |
| Jeff Bennett | 34.0 | 2 | 4 | 3.18 | 0 | 0 | 23 | 21 | 0.316 |
| Manuel Corpas | 33.2 | 1 | 3 | 5.88 | 1 | 3 | 24 | 7 | 0.326 |
| Dontrelle Willis | 33.2 | 1 | 4 | 7.49 | 0 | 0 | 17 | 28 | 0.294 |
| Chris Pérez | 33.1 | 0 | 1 | 4.32 | 1 | 3 | 38 | 12 | 0.205 |
| Joel Hanrahan | 32.2 | 1 | 3 | 7.71 | 5 | 10 | 35 | 14 | 0.342 |
| Elmer Dessens | 32.2 | 0 | 0 | 3.31 | 0 | 0 | 14 | 10 | 0.211 |
| Sean Burnett | 32.1 | 1 | 2 | 3.06 | 1 | 2 | 23 | 15 | 0.200 |
| Luis Ayala | 32.1 | 1 | 2 | 4.18 | 0 | 3 | 21 | 8 | 0.306 |
| Yorman Bazardo | 32.0 | 1 | 3 | 7.88 | 0 | 0 | 17 | 22 | 0.296 |
| Jeff Manship | 31.2 | 1 | 1 | 5.68 | 0 | 0 | 21 | 15 | 0.310 |
| Joel Hanrahan | 31.1 | 0 | 1 | 1.72 | 0 | 0 | 37 | 20 | 0.204 |
| Joel Zumaya | 31.0 | 3 | 3 | 4.94 | 1 | 7 | 30 | 22 | 0.274 |
| Matt Belisle | 31.0 | 3 | 1 | 5.52 | 0 | 0 | 22 | 5 | 0.280 |
| Fu-Te Ni | 31.0 | 0 | 0 | 2.61 | 0 | 2 | 21 | 11 | 0.187 |
| Neftali Feliz | 31.0 | 1 | 0 | 1.74 | 2 | 3 | 39 | 8 | 0.124 |
| Rafael Betancourt | 30.2 | 1 | 2 | 3.52 | 1 | 3 | 32 | 15 | 0.225 |
| Rafael Rodríguez | 30.2 | 0 | 1 | 5.58 | 0 | 2 | 10 | 9 | 0.356 |
| Collin Balester | 30.1 | 1 | 4 | 6.82 | 0 | 0 | 20 | 14 | 0.281 |
| Carlos Silva | 30.1 | 1 | 3 | 8.60 | 0 | 0 | 10 | 11 | 0.323 |
| Claudio Vargas | 30.1 | 1 | 0 | 1.78 | 0 | 2 | 20 | 11 | 0.175 |
| Hong-Chih Kuo | 30.0 | 2 | 0 | 3.00 | 0 | 1 | 32 | 13 | 0.198 |
| Joe Martinez | 30.0 | 3 | 2 | 7.50 | 0 | 0 | 19 | 12 | 0.351 |
| Rodrigo Lopez | 30.0 | 3 | 1 | 5.70 | 0 | 0 | 19 | 11 | 0.339 |
| Scott Eyre | 30.0 | 2 | 1 | 1.50 | 0 | 0 | 22 | 16 | 0.206 |
| Jack Taschner | 29.1 | 1 | 1 | 4.91 | 0 | 1 | 19 | 20 | 0.317 |
| J.J. Putz | 29.1 | 1 | 4 | 5.22 | 2 | 4 | 19 | 19 | 0.257 |
| Luke French | 29.1 | 1 | 2 | 3.38 | 0 | 0 | 19 | 11 | 0.275 |
| Cla Meredith | 28.2 | 0 | 0 | 3.77 | 0 | 0 | 17 | 12 | 0.252 |
| Ryan Sadowski | 28.1 | 2 | 4 | 4.45 | 0 | 0 | 17 | 17 | 0.264 |
| John Bale | 28.1 | 0 | 1 | 5.72 | 1 | 5 | 24 | 18 | 0.296 |
| Carlos Torres | 28.1 | 1 | 2 | 6.04 | 0 | 0 | 22 | 17 | 0.286 |
| Logan Kensing | 28.0 | 1 | 1 | 8.68 | 1 | 3 | 12 | 12 | 0.342 |
| Brian Shouse | 28.0 | 1 | 1 | 4.50 | 0 | 1 | 17 | 7 | 0.277 |
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