| MLB Pitching Statistics | |||||||||
| Player | IP | W | L | ERA | SV | SVO | K | BB | BAVG |
| Russ Springer | 41.2 | 0 | 1 | 4.10 | 0 | 1 | 47 | 14 | 0.299 |
| Jason Grilli | 26.1 | 2 | 2 | 4.78 | 0 | 0 | 27 | 14 | 0.216 |
| José Veras | 24.2 | 1 | 2 | 4.38 | 0 | 0 | 22 | 14 | 0.213 |
| Joel Hanrahan | 32.2 | 1 | 3 | 7.71 | 5 | 10 | 35 | 14 | 0.342 |
| Saul Rivera | 38.1 | 1 | 3 | 6.10 | 0 | 1 | 21 | 14 | 0.310 |
| Collin Balester | 30.1 | 1 | 4 | 6.82 | 0 | 0 | 20 | 14 | 0.281 |
| Clay Condrey | 42.0 | 6 | 2 | 3.00 | 1 | 2 | 25 | 14 | 0.233 |
| José Veras | 25.2 | 3 | 1 | 5.96 | 0 | 0 | 18 | 14 | 0.235 |
| Ken Takahashi | 27.1 | 0 | 1 | 2.96 | 0 | 0 | 23 | 14 | 0.235 |
| Kyle Farnsworth | 37.1 | 1 | 5 | 4.58 | 0 | 2 | 42 | 14 | 0.287 |
| Trevor Hoffman | 54.0 | 3 | 2 | 1.83 | 37 | 41 | 48 | 14 | 0.183 |
| Brian Matusz | 44.2 | 5 | 2 | 4.63 | 0 | 0 | 38 | 14 | 0.292 |
| Casey Janssen | 40.0 | 2 | 4 | 5.85 | 1 | 1 | 24 | 14 | 0.341 |
| Huston Street | 61.2 | 4 | 1 | 3.06 | 35 | 37 | 70 | 13 | 0.194 |
| Hong-Chih Kuo | 30.0 | 2 | 0 | 3.00 | 0 | 1 | 32 | 13 | 0.198 |
| Scott Downs | 46.2 | 1 | 3 | 3.09 | 9 | 13 | 43 | 13 | 0.251 |
| George Sherrill | 41.1 | 0 | 1 | 2.40 | 20 | 23 | 39 | 13 | 0.219 |
| Scott Schoeneweis | 24.0 | 1 | 2 | 7.13 | 0 | 3 | 14 | 13 | 0.287 |
| Jo-Jo Reyes | 27.0 | 0 | 2 | 7.00 | 0 | 0 | 21 | 13 | 0.262 |
| Sean Burnett | 25.1 | 1 | 1 | 3.20 | 0 | 1 | 20 | 13 | 0.157 |
| Wade Davis | 36.1 | 2 | 2 | 3.72 | 0 | 0 | 36 | 13 | 0.243 |
| Sergio Mitre | 51.2 | 3 | 3 | 6.79 | 0 | 0 | 32 | 13 | 0.321 |
| Joe Smith | 34.0 | 0 | 0 | 3.44 | 0 | 1 | 30 | 13 | 0.236 |
| Tim Hudson | 42.1 | 2 | 1 | 3.61 | 0 | 0 | 30 | 13 | 0.295 |
| Tom Gorzelanny | 38.1 | 4 | 2 | 5.63 | 0 | 0 | 40 | 13 | 0.262 |
| Cla Meredith | 36.2 | 4 | 2 | 4.17 | 0 | 3 | 20 | 13 | 0.324 |
| John Grabow | 25.0 | 0 | 0 | 3.24 | 0 | 0 | 16 | 12 | 0.209 |
| Cla Meredith | 28.2 | 0 | 0 | 3.77 | 0 | 0 | 17 | 12 | 0.252 |
| Vicente Padilla | 39.1 | 4 | 0 | 3.20 | 0 | 0 | 38 | 12 | 0.252 |
| Mariano Rivera | 66.1 | 3 | 3 | 1.76 | 44 | 46 | 72 | 12 | 0.197 |
| Kris Benson | 22.1 | 1 | 1 | 8.46 | 0 | 0 | 11 | 12 | 0.340 |
| Jorge Sosa | 22.1 | 2 | 1 | 6.45 | 2 | 2 | 17 | 12 | 0.311 |
| Freddy García | 56.0 | 3 | 4 | 4.34 | 0 | 0 | 37 | 12 | 0.259 |
| Kevin Mulvey | 23.0 | 0 | 3 | 7.04 | 0 | 0 | 18 | 12 | 0.264 |
| Clayton Mortensen | 27.2 | 2 | 4 | 7.81 | 0 | 0 | 11 | 12 | 0.319 |
| Alan Embree | 24.2 | 2 | 2 | 5.84 | 0 | 3 | 12 | 12 | 0.292 |
| Logan Kensing | 28.0 | 1 | 1 | 8.68 | 1 | 3 | 12 | 12 | 0.342 |
| Brent Leach | 20.1 | 2 | 0 | 5.75 | 0 | 0 | 19 | 12 | 0.213 |
| Joe Martinez | 30.0 | 3 | 2 | 7.50 | 0 | 0 | 19 | 12 | 0.351 |
| Joel Peralta | 24.2 | 0 | 3 | 6.20 | 0 | 1 | 22 | 12 | 0.278 |
| Blaine Boyer | 37.0 | 0 | 1 | 2.68 | 0 | 0 | 18 | 12 | 0.273 |
| Koji Uehara | 66.2 | 2 | 4 | 4.05 | 0 | 0 | 48 | 12 | 0.270 |
| Chris Pérez | 33.1 | 0 | 1 | 4.32 | 1 | 3 | 38 | 12 | 0.205 |
| Leo Rosales | 45.1 | 2 | 1 | 4.76 | 0 | 0 | 31 | 12 | 0.237 |
| Eddie Bonine | 34.1 | 1 | 1 | 4.46 | 0 | 0 | 19 | 12 | 0.308 |
| Buddy Carlyle | 21.1 | 0 | 1 | 8.86 | 0 | 0 | 12 | 12 | 0.380 |
| Tony Peña | 34.0 | 5 | 3 | 4.24 | 1 | 2 | 26 | 11 | 0.295 |
| Sergio Romo | 34.0 | 5 | 2 | 3.97 | 2 | 2 | 41 | 11 | 0.233 |
| Carlos Silva | 30.1 | 1 | 3 | 8.60 | 0 | 0 | 10 | 11 | 0.323 |
| Luke French | 29.1 | 1 | 2 | 3.38 | 0 | 0 | 19 | 11 | 0.275 |
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